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I have a Mac with Yosemite (don't remember the exact version)

I used CleanMyMac today, but it broke something; after using it, I can't open most Apple applications (I can't open App Store, Mail.app, Safari, System Information; it's not working).

Opening the console, I found that the problem seems to be

24/01/15 17:35:36,253 Mail[468]: Unable to load nib file: MainMenu, exiting
24/01/15 17:35:36,255 com.apple.xpc.launchd[1]: (com.apple.mail.7700[468]) Service exited with abnormal code: 1

This happens with almost all Apple applications.

All other apps work fine; Chrome, iTunes, Finder, etc.

I need to find a solution that does not involve bringing the computer to the Apple store; I have a lot of exams in these days and I need my Mac to study.

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Just to let you know, I solved the problem by reinstalling the operating system.

This can't be done directly from the app store (because it was not working)

Instead restart the mac and when the grey screen comes press Cmd + R; then connect to the internet and reinstall it.

I did a backup of my data beforehand but fortunately I didn't need it as all my files were in place.

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    Very nice solution. You could have tried downloading a combo updater, but reinstalling the OS is the best surefire way to fix this. Kudos and thanks for documenting your fix. Best of luck in the exams.
    – bmike ♦
    Commented Jan 24, 2015 at 19:54
  • This fixed the error message in my console. Afterward I had the problem of the error dialog displaying off screen. I only noticed this when I plugged in my thunderbolt display to connect to the network. When the display adjusted, there was my error dialog. Now I know to hit the return key when the beachball appears.
    – Bradley M Handy
    Commented Jan 29, 2015 at 16:15

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