I have 26K photos on a 64GB iPhone 7 and running iOS 12.4
How can I delete all photos en-masse? That is, removing all photos from the iPhone's Camera Roll.
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Your question doesn't full specify what you're wanting or what you've already tried, so I'm assuming you want to do this directly from your iPhone (as opposed to doing it while your iPhone is connected to a Mac/PC).
I'm also assuming you're just wanting to free up space and you've already backed up your photos. If so, you can follow these steps:
NOTE: If you're doing this to free up space, then you will also need to remove your deleted photos from the Recently Deleted album (as photos are stored there for 30 days before actually being removed from your device). You can select the Recently Deleted album from the very bottom of the Albums screen in order to remove them from there and free up space.
But if you have a Mac available and prefer to do it there: turn on iCloud photos on both, put the iPhone and Mac online, open Photos on the app.
Wait ages and ages for the Mac to show all the photos (phone uploads to iCloud, then Photos app downloads). Might not be as long if both were already enabled.
Select all the photos on the Mac with Cmd-A, press delete, answer the pop ups appropriately, go to recently deleted and repeat.