Tsclient is for terminal services (remote desktop, remote office) if you're not using a remote access app I'd be worried that it appeared, slim chance but it could be malicious. It's also conceivable it could be getting used as a temporary location for incomplete files by your FTP client but you didn't say what you were using.

Anyone know if a folder name can be matched regardless of path? ie. ignore sub-folder /nospotlight in every parent folder, /folder1/nospotlight, /folder2/nospotlight....

I've deteremined that hiding my repos from spotlight does indeed speed things up tremendously. With them included All My Files reports nearly 500,000 files found, with them out 30,000 files and it open instantly. So the answer I guess is just "yes", but I don't have a fix other than removing the one things I actually WANT indexed. (and FYI, nothing wrong with mds, mdworker, spotlight database, all checked and rebuilt, not errors)

I'm only referring to a new finder window, or switching to "All My Files" on an existing finder window. I noticed that other Q and thought it was a different issue, but now thinking it's related, maybe All My Files is just always slow... Thanks for the confirmation that spotlight doesn't index invisible/hidden files, figured but better to know

Thanks, It worked! I finally found a couple KB articles on VMWare site (very hard to find via search) that I added to your answer.