So Installed the `security update 2017-001` for mac OS X High Sierra on and my clipboard is broken now. I am admin. It is systemwide.    

* reset
* check the 'V' and cmd button work and use the menu option.
* disable CopyClip app at start-up
* enable guest user, log-in as them
* safe mode
* killing and pkilling pboard process (sudo too)
* freeing HDD memory as it was getting very low. Now 10/256 GB.
* zapped P-RAM
* reset SMC
* snooped in /private/tmp

It works in recovery mode —I do not have time machine enabled or the spare memory to backup ATM.

The install of the update was only slightly odd. As in it did not ask to reset the machine. After accepting the update request, I proceeded to shut down stuff and Matlab was crashed. The terminal was ssh'ed into a pi and office and pycharm were open.

The best lead I have is an abort signal for the launch control:   
 
     $ launchctl list | grep pboard
     1234 -6 com.apple.pboard
     $ id -u
     501
     $ launchctl debug gui/501/com.apple.pboard
     Configuration failed: 150: System integrity Protection is enabled 

That is the launch deamon cannot start it (-6). In recovery mode, where it works, the status is 0. System integrity protection was always enabled.         
BTW, on the update to HighSierra my Office had the unicode bug, which was fixed by a reinstall. After which all worked fine.