After some investigation, I found it's a recent behavior change in macOS Monterey, not Chrome. All Apple apps changed the pervious cmd-ctrl-f shortcut to fn(globe)-f. And Apple changed their document, take [Books][1] for example. [![enter image description here][2]][2] [1]: https://support.apple.com/en-sg/guide/books/ibk0a716cf4-9a70-485b-9835-72e3c7ed6c29/4.1/mac/12.0 [2]: https://i.sstatic.net/cuKa2.png