We're trying to decide how much effort to put into ensuring that our software works well in 32-bit mode. (It's scientific software that must handle large datasets, so ensuring that it works well does not only mean building universal binaries, but also designing around address-space limitations.)
Q: In what year were the last Macs sold that, out of the box, could not run 64-bit applications?
By "out of the box," I mean in the hands of naïve users that do not upgrade the OS, choose different kernels, or change the system configuration from the default in any significant way.