I'm a big iTerm user with 3 split panes on a 30" monitor. The only issue is that I sometimes want to add a Safari window as the left most pane. I can achieve this by using any of the window sizers out there and setting the window to float on top. However, this means that I have to Command ⌘-Tab to get to the Safari window while I ⌘+arrow to switch between the panes.
Is there a program that not only uses a grid for positioning/sizing, but also provides directional navigation between panes?