I have ordered a new 27" iMac with macOS Mojave. I use 64-bit version of Adobe CS6.

Will macOS Mojave run it?

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    Mojave still supports 64 bit apps, so I don't believe that qualifier is relevant. Note this is probably the last version in which they will work, despite being 64 bit. I tested booting with the -no32exec boot arg, and CS6 wouldn't launch. :( – Wowfunhappy Nov 7 '18 at 16:41

As noted in this answer, you should be able to run Adobe CS6 in macOS Mojave 10.14.

Another user shared their experience here and was able to use CS6 fine.

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