I have also see errors in Console when system services try to open
/Library/Sophos Anti-Virus/Sophos.keychain which is a non-existant file. I've even tried recreating a file in that path followed by
sudo security delete-keychain "/Library/Sophos Anti-Virus/Sophos.keychain" but the entry still remains in the list of keychains.
How can I remove this annoying Sophos leftover?
(can't remember which Sophos edition I originally installed, maybe it was called "Home", maybe that is the only one for Mac)