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After clean installing Yosemite and rebooting my MacBook Pro, audio seems to be deactivated, although the sound is active and I can use it. But I can't change the volume. The icon in the menu bar is grayed out:

enter image description here

If I run

sudo killall coreaudiod

in the terminal, it is activated and I can use it as usual again.

What could cause the problem and how can I fix it?

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Have you tried a NVRAM and SMC reset?

  • Yes, no luck. I even tried another clean install. Same problem. – John Sep 27 '15 at 13:01

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