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Almost as soon as I open Outlook 2011, Avast pops up with it's shield warning:

enter image description here

That's MSIL:GenMalicious-ALS [Trj].

Outlook has then "encountered an error and needs to close"; too quickly for me to determine which message this is an attachment to.

I can delete the file from ~/Library/Caches/TemporaryItems/Outlook Temp, but it just downloads and happens again.

I'm still pretty new to Mac - so I'm not as sure how to deal with this as on Windows. What can I do to stop Outlook re-downloading it, or how can I safely stop Avast quitting Outlook?

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    Interestingly I just started getting the same error! I am considering putting in a path exclusion in Avast for that temp folder to see if that bypasses it temporarily but concerned if this is a true infection. – user93001 Sep 30 '14 at 15:30
  • One of my end users just had this issue. Removing it 3 times and relaunching Outlook 3-4 times resolved it for them. I wasn't there to witness it but I did look at the logs and confirm that it happened. I'm not adding this as answer since it seems a little too flaky of a solution, might help someone though. – Mr Rabbit Sep 30 '14 at 19:15
  • @MrRabbit Hmm, I've tried it a few more in vain hope, but no luck so far. – OJFord Sep 30 '14 at 19:48
  • Just to add to this, my user called back with it reoccurring. The "kcal-whatever" file that it is flagging and quarantining seems to be a normal temporary file that appears (then disappears) whenever Outlook is connecting to the email server. In the end I went with the assumption that it's a false positive hit and just added ~/Library/Caches/TemporaryItems/Outlook Temp to the list of exclusions in Avast. – Mr Rabbit Sep 30 '14 at 20:30
  • I'm having exactly the same thing. Most likely false positive – Chris Byatt Oct 1 '14 at 8:28

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