To the best of my knowledge, the answer is no. Of course, without trying out every single mouse app in the App Store, I can't be 100% certain.
I can tell you that I've been a long time user of Mobile Mouse. They have about the best mouse/remote control app I've found. They put a lot of effort into trying to get the app to work like a real mouse, and eventually decided that it couldn't be done, at least not with an acceptable level of performance (see FAQ #6). They decided on the "air mouse" mode instead, and though it doesn't work like a real mouse, it does work very well for what it is.
Best of luck in your search, and of course if you do find such an app, please let us know!