Per your comment that "a way to delete the browser cache completely" may be suitable, you can go to the Chrome menu → Settings → Privacy and clear the cache.
Yep. Maybe first you should clean up Chrome browser cache and some temporary files, and see how it goes.
IMO it sounds like client side caching is not your problem. It's more likely you're running into a server side cache problem. If you're using a CDN (cloudflare, cloudfront, etc.) to serve assets, make absolutely sure that you're expiring assets appropriately.
Barring that, I recommend using Chrome in Incognito mode which does not persist a long lived client cache.