boot up the system in "macOS Recovery HD" where SIP restrictions are not enforced (according to @user3439894 ) , and basically run in a terminal

sudo find /Applications/iTunes.app/ -depth -print0 | sudo xargs -0 chmod a-x

and reboot into mac. it basically recursively remove the executable flag on every file in /Applications/iTunes.app , which should stop MacOS from ever starting iTunes (the normal way), which effectively makes iTunes disabled.

boot up the system in an Ubuntu CD/usb drive, and basically run in a terminal

sudo su
mkdir /mount
mount /dev/nvme0n1p1 /mount
find /mount/Applications/iTunes.app/ -depth -print0 | xargs -0 chmod a-x

• you have to change /dev/nvme0n1p1 with wherever the root partition is, and if you don't know, you can launch gparted with the command sudo gparted which can help you find out by matching the size of your MacOS root partition with every partition in the system. but if you're using an NVMe disk, it's probably /dev/nvme0n1p1

• this probably won't work if your MacOS partition is encrypted..

boot up the system in "macOS Recovery HD" where SIP restrictions are not enforced (according to @user3439894 ) , and basically run in a terminal

sudo find '/Volumes/Macintosh HD/Applications/iTunes.app' -depth -print0 | sudo xargs -0 chmod a-x

and reboot into mac. it basically recursively remove the executable flag on every file in /Applications/iTunes.app , which should stop MacOS from ever starting iTunes (the normal way), which effectively makes iTunes disabled.

boot up the system in an Ubuntu CD/usb drive, and basically run in a terminal

sudo su
mkdir /mount
mount /dev/nvme0n1p1 /mount
find /mount/Applications/iTunes.app/ -depth -print0 | xargs -0 chmod a-x

• you have to change /dev/nvme0n1p1 with wherever the root partition is, and if you don't know, you can launch gparted with the command sudo gparted which can help you find out by matching the size of your MacOS root partition with every partition in the system. but if you're using an NVMe disk, it's probably /dev/nvme0n1p1

• this probably won't work if your MacOS partition is encrypted..

boot up the system in an Ubuntu CD/usb drive, and basically run in a terminal

sudo su
mkdir /mount
mount /dev/nvme0n1p1 /mount
find /mount/Applications/iTunes.app/ -depth -print0 | xargs -0 chmod a-x

and reboot into mac. it basically recursively remove the executable flag on every file in /Applications/iTunes.app , which should stop MacOS from ever starting iTunes (the normal way), which effectively makes iTunes disabled.

• you have to change /dev/nvme0n1p1 with wherever the root partition is, and if you don't know, you can launch gparted with the command sudo gparted which can help you find out by matching the size of your MacOS root partition with every partition in the system. but if you're using an NVMe disk, it's probably /dev/nvme0n1p1

boot up the system in "macOS Recovery HD" where SIP restrictions are not enforced (according to @user3439894 ) , and basically run in a terminal

sudo find /Applications/iTunes.app/ -depth -print0 | sudo xargs -0 chmod a-x

and reboot into mac. it basically recursively remove the executable flag on every file in /Applications/iTunes.app , which should stop MacOS from ever starting iTunes (the normal way), which effectively makes iTunes disabled.

boot up the system in an Ubuntu CD/usb drive, and basically run in a terminal

sudo su
mkdir /mount
mount /dev/nvme0n1p1 /mount
find /mount/Applications/iTunes.app/ -depth -print0 | xargs -0 chmod a-x

• you have to change /dev/nvme0n1p1 with wherever the root partition is, and if you don't know, you can launch gparted with the command sudo gparted which can help you find out by matching the size of your MacOS root partition with every partition in the system. but if you're using an NVMe disk, it's probably /dev/nvme0n1p1

• this probably won't work if your MacOS partition is encrypted..