Hot answers tagged microphone
To disable iSight and other cameras, use: sudo kextload /System/Library/Extensions/AppleCameraInterface.kext (tested on 10.9) I'm not aware of a way to disable audio input without affecting output. It's the same hardware so unloading/removing the kext probably won't work. One step you can take is to turn the input volume down to zero in your sound ...
I think you can specifically target your iSight camera by (re)moving /System/Library/QuickTime/QuickTimeUSBVDCDigitizer.component According to this: http://www.macosxhints.com/article.php?story=20070323094959262 The link does mention that it is 10.4 specific and I haven't tried it under 10.8/10.9 but it's a good place to start.
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