I have two Logitech MX510 mice, and two macs - an iMac and MBP. Recently, the former has started responding to mouse input jerkily and without any precision - to the point that it is almost unusable. Switching out the mouse, rebooting, etc make no difference.
Similarly, both mice function fine over a long period of time attached to the MBP. The only change I have made to the iMac (2012 gen, OSX10.8) is to install Crashplan - but I did this on the other computer too and that made no difference.
Is there anything I can do to flush out the settings for the mouse, and so return it to usability? The problem does not occur with the wireless magic mouse, or the wireless trackpad.