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I do not have a comparison between the OS X versions but after I switched to a 15" retina MBP and simultaneously to OS X 10.8 the Preview app takes a long time to open pdfs with lots of vectors inside. Also, scrolling is slow, once the file is opened. I did not run into this problem with my old MBP (mid 2007) and 10.7.

Does anyone know a solution or the reason for this problem and whether it is being dealt with?

Here is an example file that causes this problem: https://dl.dropboxusercontent.com/u/119251/methods-rhythmcycle.pdf

edit: Is anyone able to replicate the described phenomenon with the above supplied file?

edit2: Can someone please try to open the file with a rMBP (preferably 15")?

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Did you update your OS to 10.8.3 ? –  Matthieu Riegler May 6 '13 at 12:14
Yes, sorry for not mentioning it in the text. –  simmmons May 6 '13 at 12:28
Is Adobe Reader a lot faster? –  Tom Gewecke May 6 '13 at 12:51
Yes, Adobe Reader works perfectly. –  simmmons May 6 '13 at 13:02
Just tried it works purfectly with Preview on MacBook Air os x 10.8.3 –  Buscar웃 May 7 '13 at 9:47

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