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I use "Best for Retina display" in my settings. It's suitable for my eyes:)

But I'd like to get more spaces in some applications by using the highest resolution. So is there a way to do so?

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As in have different applications running at different resolutions at the same time? – Warren Pena May 6 '13 at 2:20
@Pena Yes, that's it! Do you have any idea? – nickcheng May 6 '13 at 3:04
No, so far as I know, you can't do that. – Warren Pena May 6 '13 at 3:05

The OS doesn't have any sort of procedure to tell app A to use one screen size and app B another.

Unless the apps you use have a preference to change layout, icon size or other aspects of layout and zoom (like a spreadsheet tool can zoom in and out regardless of the overall resolution), you'll have to pick the best resolution and then change it up as needed based on your workflow.

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