I have found that I need to run both Quicksilver and Spotlight. I consider this to be a waste of CPU and memory and would like to eliminate one of them probably Spotlight. The reason I would like to retain Quicksilver is because it is a tiny bit faster and much more flexible.
The main thing that I current use Spotlight for is searching within Mail. I use that all the time. For all the rest of opening applications and files, I use Quicksilver.
Is there a way to eliminate Spotlight without losing the searching within Mail? Or alternatively, to reduce the overhead of Spotlight but still keeping it available for searches within Mail?
An additional Quicksilver annoyance is that on Mountain Lion, Quicksilver crashes fairly frequently.