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I have a Cisco VPN client in OSX 10.6.8, which runs only in 32 bit mode.

Are there any serious disadvantages of switching to 32 bit mode permanently?

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Is the is the Cisco AnyConnect VPN client ? I'm running OS X 10.6.8 in full 64 bit mode with version 2.5.2006 of this client without any problems. –  Paul R Mar 8 '12 at 10:03
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Not inherently. 32 bit mode should run fine as long as all your drivers and binaries include a 32-bit version, which is currently the case unless you specifically downloaded 64-bit versions. It should even use a little less ram.

But:

  • Mountain Lion will be 64-bit only, so I don't expect universal binaries to include 32-bit versions forever.
  • I have "slimmed" all my binaries to delete the 32-bit version. If you have ever used such space-saving utilities, the slimmed apps won't work.
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Are there any limitations as to Physical memory? –  Adam Matan Mar 8 '12 at 8:58
    
No, it will support whatever your hardware does. (More on the difference) –  David Veksler Mar 8 '12 at 9:07
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