How does one make the fonts that iTunes uses for things like app descriptions larger? I know about Universal Access -> Zoom, but I'm looking for something a little more app-specific, like web browsers have.
It is possible to to change/customize every font/font-size within iTunes.app, that is used for the menu, pop-up dialogs, view-field etc..
In order to do so navigate to
Then download ThemePark3.1 in order to open and edit the Localized.rsrc file. Once you edited the font(s)/size to your liking, you need to save your changes from within ThemePark.
It might be, that you also need to reboot first to see the changes!!
If that is also true for 10.7 (still running 10.6.8, therefore can only guess), please confirm this information!! Basically "simple" images can be drawn and rendered from code instead of using single image files, in png, tiff, jpg - format.
Those .css files also manage font information, like font-style, color values, size etc...
The free application TinkerTool lets you edit system fonts and their sizes. As a bonus, you don't need to go monkeying around with system files, because TinkerTool does it for you. (It'll work for certain, and you don't need to worry about, say, deleting something you don't want to.)
OTOH, it won't let you be app-specific in your preferences, but it will let you change the size of the text.