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I use Chrome 16.0.912.75 in MacOSX 10.7.2.

A right-click on the icon of an extension will show a menu, but the left-click is unresponsive.

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thanks for edit – emj365 Jan 18 '12 at 9:16
No problem. We help here each other :) Welcome to AskDifferent! – gentmatt Jan 18 '12 at 9:30
I assume left- and right-clicking works normally everywhere else? – timothymh Jan 18 '12 at 21:23
My other pc also run chrome in macos 10.7.2 works fine. And my coworker's chrome has same problem. – emj365 Jan 29 '12 at 1:46
It happen to me as well. Have you found the solution? – eamai Mar 3 '12 at 4:40

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