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For some reason, my text to speech isn't working. I don't know why it stopped working. It works when I manually click it, but when using the default hotkey alt+esc, it doesn't do anything.

I have no idea what happened. How can I fix this? I tried changing hotkeys, but the problem persists.

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Try running Disk verify/repair. Sounds weird I know but that is what just fixed my issue. If verify doesn't tell you something is wrong then don't worry about the repair. – user18515 Feb 9 '12 at 23:47
I have the same issue constantly, and have to restart the computer each time to get it working again. – user20205 Mar 16 '12 at 1:16

I had a problem using speech with the Preview app. Turns out something went screwy after adding annotations to the specific document I was looking at and all I had to do was revert it.

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I have also experience this problem. I have found today that shutting Google Chrome and restarting it cures the problem.

Update. This happened again & restarting google chrome did not fix it. I ended up closing all my open programs & finder windows & restarting finder then it worked again. I will update this again next time it fails & try to identify the specific action that fixes it or causes it.

I have a hunch it may be connected with System Preferences, finder windows or Monitor.

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Sometimes you just need to reboot your machine. Mine sometimes just stops working. A reboot takes care of it.

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Mine stops working every time I change the systems language. The only solution I have found is restarting.

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