I already tried this:
cd ~/Downloads find . -print0 | xargs -0 xattr -d com.apple.quarantine
But it doesn't seem to work under Mac OS X 10.7 (aka. Lion) anymore:
xattr: ./cabin/Cabin-Bold.otf: No such xattr: com.apple.quarantine
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I haven't tested this under Lion but
and then restarting should totally disable this functionality.