Yes - I definitely think you can and will benefit from Lion without a touch input device.
Mission Control is entirely controlled by the keyboard and (non-touch) mouse - there's just a gesture to trigger it.
Launchpad - I really would't recommend anyone consider Launchpad at all when considering an upgrade to Lion. Compared to what's available today, it demos well, but doesn't really improve day-to-day experience enough to focus on this.
In my opinion, the most valuable features of Lion are not the gesture control, but what I dub ARV, i.e. the trinity of the Auto Save, Resume, Versions features. My guess is they haven't gotten much traction in the press because they don't demo as sexily as the counterparts you're mentioning (which are great, sure).
But the ability to just quit an application with a document you haven't even saved yet is ridiculously useful in everyday life when your desktop, task switching bar or memory are getting overburdened.
When you reboot your first time – without saving a thing – and all the applications, documents and windows you had open all return exactly where you left them... it's nearly a religious experience! :)
And Versions brings to regular users the best parts of a powerful (but heretofore complicated) tool called "version control" that software engineers have kept to themselves for over a decade. If you've ever sent (or received) an attachment via e-mail with multiple recipients asking "Please review and make changes and send back to me", then you're going wonder where this was all your life. Combined with Auto-Save creating micro-versions of your file (every time you launch, quit - or even pause typing!) - you can easily go back through the entire history of your document to find old parts you deleted by accident.
In my opinion, this is a far more important OS release than since I first got on the Mac in 2005.
Context: been using Lion since launch day, and I'm an advanced user, but my day job is designing web sites and apps for common, timid users with basic needs.